N10 系列实验室及中试型高压均质机

N10 Series Laboratory and Pilot-Scale High-Pressure Homogenizer

The exceptional performance of the N10 High-Pressure Homogenizer in applications such as particle micronization/nanonization, homogeneous dispersion, and cell disruption has garnered significant attention from leading research teams. These teams seek equipment capable of meeting both early-stage R&D requirements and pilot-scale or even full-scale production needs. In response to this demand, we introduced the N10 Series. This model features a novel, easily cleanable high-pressure cylinder design, combined with modular feeding, discharge, and temperature control units. Users can select and configure these components according to their specific needs, effectively addressing key requirements such as small batch sizes, low sample residue, and ease of cleaning during experimental stages. Additionally, we offer optional validation documentation compliant with PIC/S cGMP standards, meeting the high regulatory demands of the biopharmaceutical industry for manufacturing equipment.

Equipped with an electro-hydraulic drive system, the N10 enables efficient continuous production while offering advantages such as low noise and freedom from grinding media contamination. It is particularly suitable for preparing high-value samples, such as pharmaceuticals and novel materials. Notably, this model shares the same design principles as our production-scale units, including a fixed geometry flow path and an impingement diamond reaction chamber. This design ensures concentrated energy distribution, precise control over particle size uniformity, and excellent reproducibility. Experimental data can be easily scaled up for production. The N10 meets the demands of small-scale experimentation while offering scalability, making it an ideal solution bridging early-stage R&D and pilot-scale production.

Specifications

Pressure Range: Up to 30,000 psi (2,068 bar)

Flow Rate: Up to 320 ml/min

Minimum Sample Volume: 300 ml (with heat exchanger)

Max. Feed Temperature: 75 °C

Power Unit: Electro-hydraulic drive

Nozzle Material: Diamond, fixed geometry

Plunger Material: Ceramic

Enclosure: Stainless steel

Hold-up Volume: 70 ml (with heat exchanger)

Dimensions (W × D × H): 800 × 750 × 1300 mm

Weight: 260 kg

Utility Requirements

‧ Electrical: Three-phase 220/380 V, 60 Hz, 5 HP (3.7 kW)

‧ Cooling Water, hydraulic oil: 10 lpm @ 25 °C, PT 1/2"

‧ Cooling Water, product outlet: 20 lpm @ 16 °C, PT 1/2"

Optional Accessories

Low-temperature water bath

Spare homogenization chamber

Temperature control for homogenization chamber

Product outlet temperature controller

Spare feed cup

Pressurized feed cup

Reverse cleaning function

Validation documents

Factory acceptance and final acceptance

Explosion-proof configuration

Plunger cooling system

Extended warranty service

N10 系列实验室及中试型高压均质机

N10高压均质机在颗粒微纳米化、均质分散及细胞破碎等应用领域展现的卓越性能，已获得众多前沿研究团队的青睐。这些团队期望所购置的设备既能满足前期研发需求，又能兼顾中试乃至规模化生产的要求。为响应这一需求，我们推出了N10系列。该机型采用新型易清洗高压缸设计，搭配模块化进料区、出料区及温控单元，用户可根据实际需求选配组合，完美兼顾实验阶段对小批量、低样品残留及易清洁的核心需求。同时，我们还可提供符合PIC/S cGMP标准的验证文件选配方案，满足生物医药行业对制药设备的高规格要求。

采用电液驱动系统的N10能实现高效连续生产，兼具低噪音、无研磨介质污染等优势，特别适合药物研发及新型材料等高附加值样品的制备。值得一提的是，本机型与本公司规模化生产机型均采用相同设计原理的固定几何流道及对撞式钻石反应腔，其能量分布集中，可精准控制粒径分布的均一性与重现性，实验数据能轻松实现工艺放大。N10既满足小批量实验需求又具备量产扩展能力，是连接前期研发与中试生产的理想解决方案。

规格参数

压力范围：最高30,000 psi (2,068 bar)

流量：最高320 毫升/分钟

最小样品量：300 毫升（带热交换器）

最高进料温度：75 ℃

动力单元：电液驱动

喷嘴材质：金刚石，固定几何结构

柱塞材质：陶瓷

外壳：不锈钢

残留体积：70 毫升（带热交换器）

尺寸（宽×深×高）：800 × 750 × 1300 毫米

重量：260 公斤

公用设施要求：

‧ 电源：三相220/380伏，60赫兹，5马力（3.7千瓦）

‧ 液压油冷却水：10升/分钟 @25℃，PT 1/2"接口

‧ 出料口冷却水：20升/分钟 @16℃，PT 1/2"接口

可选配件

低温水槽

备用均质腔

均质腔温度控制

出料温度控制器

备用进料杯

加压式进料杯

反向清洗功能

验证文件

工厂验收与最终验收

防爆配置

柱塞冷却系统

延长保修服务