高压均质机最主要的两个应用是细胞破壁和高压均质
Cell Rupture（各种细胞破壁所使用的压力）     
Soft Mammalian Cells (i.e. Lymphocytes)
动物细胞（淋巴细胞）                                                            1 to 15 MPa   
Organelles & Mitrochrondia
细胞器与线粒体                                                                        1 to 15 MPa   
Parasites (Typanosomes)
寄生物（锥体虫）                                                                    1 to 15 MPa   
Sperm
                                                                                                    1 to 35 MPa   
Nematodes
线虫类                                                                                        1 to 35 MPa   
E.coli
大肠杆菌                                                                                30 to 140 MPa   
Mammalian Tissue
动物组织                                                                                70 to 150 MPa   
Vegetative Cells and Cyanobacteria
植物组织与藻类（蓝细菌）                                                35 to 150 MPa   
Yeast
酵母菌                                                                                  100 to 250 MPa   
Stratum Corneum
角质层                                                                                  140 to 200 MPa   
DNA 100 to 250 MPa   
Hard Bacteria (staphylococcus, streptococcus)
硬细菌（葡萄球菌、链球菌）                                          150 to 320 MPa   
霉菌                                                                                      150 to 320 MPa   

Homogenisation   

 
Liposomes(脂质体）                                                          20 to 150 MPa   
Microemulsions and nanoparticles（乳剂、纳米粒） 20 to 350 MPa   
Deagglomeration（凝结块、结晶）                                30 to 350 MPa   
Lipid Nanoparticles（脂质纳米粒）                                 50 to 200 MPa *   
Microbial inactivation food preservation                        200 to 400 MPa